This volume in the series methodological surveys in biochemistry and analysis is based on the proceedings of the eighth international bioanalytical forum for drugs and metabolites including anti infective agents held september 5 8 1989 in guildford surrey. The global anti infective agents market size was valued at usd 1111 billion in 2018 and is anticipated to expand at a cagr of 34 during the forecast period extensive rd efforts pertaining to the development of new drugs with high efficacy and potency against multi drug resistant micro organisms is one of the major factors stimulating the growth. Determination of antiprotozoal drug mechanisms by metabolomics approaches darren j creek 1 2 and michael p development of high resolution lc ms methods and improved data analysis software now allows rapid detection of drug induced changes to cellular metabolism in an untargeted manner plasmodium spp are the infectious agents . Analysis of drugs and metabolites in tissues and other solid matrices authors methodological surveys in biochemistry and analysis reid e wilson id eds royal soc chem cambridge uk google analysis for drugs and metabolites including anti infective agents reid e wilson id eds royal society of chemistry cambridge uk pp 207 . Inherent in this pool are cellular mechanisms associated with intermediary metabolism a prime focus of study for metabolomics approaches and a key potential strategy toward the discovery of novel molecular targets for development of anti infective agents
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